Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7808333 | Journal of Molecular Structure | 2018 | 8 Pages |
Abstract
In this work, a series of Mannich bases bearing ferrocenyl groups were synthesized via Mannich reactions. The effects of different conditions on the reaction were explored, and the newly synthesized compounds were well characterized by NMR and FT-IR. All compounds have been screened for in vitro antibacterial and antifungal, and the compounds 1-ferrocenyl-3-phenyl-3-(m-nitrophenylamino)-1-acetone (2f) and 1-ferrocenyl-3-phenyl-3-(p-nitrophenylamino)-1-acetone (2g) were shown to be significant activity against all the tested bacterial strains, such as Staphylococcus aureus, Streptococcus, Actinomycete, Escherichia coli, Saccharomyces cerevisiae.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yuting Liu, Hong Xin, Jingyi Yin, Dawei Yin, Zijiang Yang, Jie Li,