| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7809305 | Journal of Molecular Structure | 2016 | 11 Pages |
Abstract
Three gallium complexes bearing 9-anthraldehyde thiosemicarbazones have been synthesized. The three complexes displayed good cytotoxic profiles against two human colon cancer cell lines, HCT-116 and Caco-2. All three complexes bind strongly to DNA via non-classical intercalation and also bind strongly to human serum albumin. Computational docking studies show the complexes bind in the major grove of DNA.342
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Authors
Floyd A. Beckford, Alyssa Brock, Antonio Gonzalez-SarrÃas, Navindra P. Seeram,