| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7809955 | Journal of Molecular Structure | 2014 | 13 Pages |
Abstract
- MicroScale Thermophoresis (MST) measures dissociation constants down to 1 picomolar.
- MST can dissect different binding mechanism by distinct thermophoresis signals.
- MST quantifies dissociation constants in 100% cell lysate.
- MST can be used to determine thermodynamic parameters for interactions.
- MST can be used to monitor enzyme kinetics and protein folding.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Moran Jerabek-Willemsen, Timon André, Randy Wanner, Heide Marie Roth, Stefan Duhr, Philipp Baaske, Dennis Breitsprecher,