Model selection for high b-value diffusion-weighted MRI of the prostate

DK and SE models best fit DWI data in PZ and PCa, and non-ME models consistently outperformed the ME model. Voxel-wise mapping of the preferential model demonstrated that the vast majority of voxels in either tissue type were best fit with one of the non-monoexponential models. At the given SNR levels, the maximum b-value of 2000 s/mm2 is not sufficiently high to identify the preferred non-monoexponential model.