Evaluation of glioblastoma (U87) treatment with ZnO nanoparticle and X-ray in spheroid culture model using MTT assay

In treatment of glioblastoma cell lines U87, using ZnO nanoparticles with the density of 10 mM can be an alternative for 2, 4, and 6 Gy doses of X-ray 6 MV. This result is very important for the protection of normal tissues to radiation therapy. Adding 2, 4, and 6 Gy doses of X-ray after treating ZnO nanoparticles for one VDT did may not lead to higher efficiency of ZnO nanoparticles.