Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8262964 | Experimental Gerontology | 2015 | 17 Pages |
Abstract
Cellular senescence was initially described as the phenomenon of limited cell divisions that normal cells in culture can undergo during long-term-cultivation. Later it was found that senescence may be induced by various stress factors. The intriguing resemblance between stress-induced and replicative senescence makes questionable the distinction between both types and suggests that the cellular senescence is a common outcome of stress response. Growing evidences support the idea that stress-induced senescence is the cell-type specific.
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Authors
Irina Fridlyanskaya, Larisa Alekseenko, Nikolay Nikolsky,