| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8263253 | Experimental Gerontology | 2015 | 8 Pages |
Abstract
Our results indicate that respirometric profiles of readily obtainable blood cells are associated with physical function and strength. Future studies should be undertaken in order to determine whether blood-based bioenergetic profiling can provide an objective index of systemic mitochondrial health.
Keywords
DXAFCCPIL-6PBMCSRCOCRAdenosine TriphosphateATPinflammationinterleukin-6ELISAEnzyme-linked immunosorbent assaydual energy X-ray absorptiometryBloodelectron transport chainBioenergeticsPeripheral blood mononuclear cellbody mass indexBMIextracellular fluxspare respiratory capacityPhysical functionMitochondriaOxygen consumption rateETcKnee extensor
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Authors
Daniel J. Tyrrell, Manish S. Bharadwaj, Cynthia G. Van Horn, Anthony P. Marsh, Barbara J. Nicklas, Anthony J.A. Molina,