Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8263687 | Experimental Gerontology | 2015 | 12 Pages |
Abstract
This work analyzes load-induced metabolic, vascular and T2 changes in low back muscles of healthy, young and late-middle-aged subjects by combining 31P-CSI, T2- and diffusion-weighted MRI. In addition anatomic MRI was applied to determine age-related changes in muscle cross-sectional area and fat infiltration. Finally, derived parameters were compared to each other and showed some interesting associations that may provide new insights into muscle physiology during healthy aging.
Keywords
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Ageing
Authors
Patrick Hiepe, Alexander Gussew, Reinhard Rzanny, Eduard Kurz, Christoph Anders, Mario Walther, Hans-Christoph Scholle, Jürgen R. Reichenbach,