Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8263755 | Experimental Gerontology | 2015 | 11 Pages |
Abstract
Neither a single nor a combined set of tested biomarkers reflected the presence of dynapenia or sarcopenia in elderly women. However, due to the associations of IGF-1 and GDF-15 with correlates of muscle mass and function, these parameters remain promising candidates in a potential set of blood-based biomarkers to diagnose sarcopenia and/or dynapenia.
Keywords
FGFBIADXAPTEIGF-1RDynapeniaIGF-1IGFBPGDF-15GDF-8EWGSOPTGF-βSkeletal muscle atrophyMRIinsulin-like growth factor-1Serum biomarkerstransforming growth factor-βBioelectric impedance analysisMagnetic resonance imagingdual-energy X-ray absorptiometrybody mass indexBMIfibroblast growth factorBMPbone morphogenic proteinEuropean Working Group on Sarcopenia in Older PeopleType 1 insulin-like growth factor receptor
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Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Marlene Hofmann, Barbara Halper, Stefan Oesen, Bernhard Franzke, Petra Stuparits, Harald Tschan, Norbert Bachl, Eva-Maria Strasser, Michael Quittan, Martin Ploder, Karl-Heinz Wagner, Barbara Wessner,