| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8264409 | Experimental Gerontology | 2014 | 8 Pages |
Abstract
The objective of this review is to discuss recent advances in: (i) the potential cellular and molecular basis of Frailty Syndrome, including development of new models to study it; (ii) the human and animal measures of Frailty Syndrome; and (iii) the development of objective cross-species correlates to aid the basic understanding, diagnosis, treatment and rehabilitation of Frailty Syndrome in older adults.
Keywords
TNFNF-kBIGFPBMCRheumatoid arthritisHumaninterferonIFNinterleukinchronic kidney diseaseAnimalDiabetes mellitusCVDFrailtyperipheral blood mononuclear cellsfrailty syndromeCMVcytomegalovirusInsulin-like growth factortumor necrosis factornuclear factor kappa-light-chain-enhancer of activated B cellsReviewMeasuresCKDSyndromeC-reactive proteinCRPchemokine (C-X-C motif) ligand 1
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Authors
M. Jane Mohler, Mindy J. Fain, Anne M. Wertheimer, Bijan Najafi, Janko Nikolich-Žugich,