| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8264689 | Experimental Gerontology | 2014 | 7 Pages |
Abstract
Our 1H NMR-based metabolomic approach was able to characterize the effect of age on urinary and fecal metabotypes. The implementation of this analytical strategy may increase our understanding of the metabolic alterations involved in the aging process and assist in the design of anti-aging interventions.
Keywords
NNMTPBSDQ2nicotinamide N-methyltransferasePLS-DATCASAMTSPVIP1-methylnicotinamideTamm–Horsfall proteinAUROCNMCTHPnuclear magnetic resonanceS-adenosylmethioninevariable importance in projectionpartial least squares-discriminant analysisNMRMetabolic footprintMass spectrometryPhosphate buffered salineMetabolomelatent variablearea under the ROC curveMetabolic profilingSenescence
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Riccardo Calvani, Elisa Brasili, Giulia Praticò, Giorgio Capuani, Alberta Tomassini, Federico Marini, Fabio Sciubba, Alberto Finamore, Marianna Roselli, Emanuele Marzetti, Alfredo Miccheli,