9-Norbornyl-6-chloropurine (NCP) induces cell death through GSH depletion-associated ER stress and mitochondrial dysfunction

Article ID	Journal	Published Year	Pages	File Type
8267600	Free Radical Biology and Medicine	2016	37 Pages	PDF

Keywords

CDNB 1,1,3,3-tetraethoxypropane MDA NRF-2 NCP ABT 4-PBA CCCP l-glutathione reduced DPI TFA GSSG GST GSH MMP CAPE TBA 1-aminobenzotriazole 2-Thiobarbituric acid allopurinol EDTA Ethylenediaminetetraacetic acid Trifluoroacetic acid Sulfosalicylic acid caffeic acid phenethyl ester QUER ALLO Apoptosis diphenyleneiodonium chloride sodium phenylbutyrate lipoxygenase Unfolded protein response Mitochondrial membrane potential Propidium iodide Carbonyl cyanide 3-chlorophenylhydrazone Quercetin Glutathione glutathione-S-transferase glutathione reductase Reactive oxygen species

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Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

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9-Norbornyl-6-chloropurine (NCP) induces cell death through GSH depletion-associated ER stress and mitochondrial dysfunction

Authors

Pavla PlaÄková, Michal Å ála, Markéta Å mÃdková, Milan Dejmek, Hubert HÅebabeckÃ½, Radim Nencka, Hendrik-Jan Thibaut, Johan Neyts, Helena MertlÃková-Kaiserová,