Bidirectional regulation of NF-ÎºB by reactive oxygen species: A role of unfolded protein response

Article ID	Journal	Published Year	Pages	File Type
8270664	Free Radical Biology and Medicine	2013	13 Pages	PDF

Keywords

TRAF IRE1 XBP1 eIF2α S1P ATF6 IKK PKB NF-κB IL-1R mTORC1 TNFR GRP78 NIK PKD RIP1 Nuclear factor-E2-related factor 2 NF-κB inducing kinase ERSE DHMEQ ER stress response element UPRE PKAc PI3K PP2A LPS NEMO IκB UPR HDAC HO-1 Nrf2 ERAD c/ebpβ CCAAT/enhancer-binding protein β H/R IκB kinase PKR-like ER kinase inositol-requiring enzyme 1 Endoplasmic reticulum stress Ultraviolet ER-Associated Degradation CHOP Site-1 protease endoplasmic reticulum eukaryotic translation initiation factor 2α TNF receptor-associated factor nuclear factor-κB Keap-1 Phosphatidylinositol 3-kinase activating transcription factor 6 lipopolysaccharide NF-κB essential modulator inhibitor of NF-κB Mammalian target of rapamycin complex 1 heme oxygenase 1 histone deacetylase hypoxia/reoxygenation Unfolded protein response X-box-binding protein 1 protein phosphatase 2A Kelch-like ECH-associated protein 1 CCAAT/enhancer-binding protein homologous protein Protein kinase B (AKT)protein kinase D receptor interacting protein 1 PERK SHIP-1 Reactive oxygen species interleukin-1 receptor tumor necrosis factor receptor

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Bidirectional regulation of NF-ÎºB by reactive oxygen species: A role of unfolded protein response

Authors

Shotaro Nakajima, Masanori Kitamura,