| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8287501 | Acta Histochemica | 2018 | 9 Pages |
Abstract
In conclusion, we have demonstrated that melatonin stimulated α-cell production, increased the number of pancreatic islets and caused a decrease in total lipids, whereas cART increased serum haemoglobin and decreased various parameters of the nephron in an HIV-free rat model, suggestive of tubular dysfunction.
Keywords
LPLCARTNHSAphAPFAFTCALTDPXVLDLTDFTBSEFVFFANGSEmtricitabineRenal corpuscleEGFRDABPBSNRTINNRTIPCTsproximal convoluted tubulesIgGEfavirenzH&EROSASTAlanine aminotransferasePeriodic Acid SchiffFree fatty acidsstandard deviationIHCImmunohistochemistryimmunoglobulin GBETAanalysis of varianceANOVAaspartate transaminaseTris buffered salinetenofovir disoproxil fumaratePancreatic isletsstandard error of the meancombination antiretroviral therapynormal horse serumnormal goat serumAlpha cellBeta cellsPhosphate buffered salineLipoprotein lipaseLow-density lipoproteinLDLvery low-density lipoproteinsSEMestimated glomerular filtration ratePAShaematoxylin and eosinHistopathologyhuman immunodeficiency virusHIVparaformaldehydeControlglomerulusReactive oxygen speciesMelatonin receptor
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Authors
Danélle Truter, Nireshni Chellan, Hans Strijdom, Ingrid Webster, Jordyn Rawstorne, Sanet H. Kotzé,