Article ID Journal Published Year Pages File Type
8290300 Archives of Biochemistry and Biophysics 2014 9 Pages PDF
Abstract
Myocardin (MYOCD), a co-transcriptional activator of serum response factor (SRF), stimulates the expression of smooth muscle (SM) genes and inhibits the cell cycle. In addition to its roles in the development, MYOCD may be critically involved in the pathogenesis of proliferative vascular diseases. This review mainly focuses on how MYOCD activity is regulated and how it inhibits cell proliferation.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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