| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8290463 | Archives of Biochemistry and Biophysics | 2013 | 16 Pages |
Abstract
- Sub-micellar SDS concentration rapidly induces fibrillization of SB at pH 2.0.
- Bis-ANS is about 3-fold more potent inhibitor of SB fibrillation than ANS.
- H-bonding and Ï-Ï interactions are evident in binding of ANS and bis-ANS to SB.
- Ionic interactions play negligible role in binding of naphthalene derivatives to SB.
- Inhibition may be due to disrupted Ï-Ï interactions and inter-polypeptide repulsion.
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Authors
Atiyatul Qadeer, Ejaz Ahmad, Masihuz Zaman, Mohd Wasif Khan, Javed Masood Khan, Gulam Rabbani, Khaja Faisal Tarique, Gaurav Sharma, Samudrala Gourinath, Sajid Nadeem, Gamal Badr, Rizwan Hasan Khan,