Acetylsalicylic acid (aspirin) and salicylic acid interaction with the human erythrocyte membrane bilayer induce in vitro changes in the morphology of erythrocytes

- Differences were observed between assayed salicylates and lipid bilayer interactions.
- Both salicylates interacted with phospholipid classes present in erythrocyte membranes.
- Results indicate that both salicylates induced fluidization of the lipid systems.