| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8290533 | Archives of Biochemistry and Biophysics | 2013 | 12 Pages |
Abstract
- Low H2O2 concentrations: fast but limited inactivation of MPO via Compound I.
- High H2O2 concentrations: complete inactivation of MPO via Compound III.
- H2O2 (⩾1000 fold molar excess) acts as a suicide substrate.
- Inactivation: destruction of heme, oxidation and disruption of protein.
Keywords
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Biochemistry
Authors
Martina Paumann-Page, Paul G. Furtmüller, Stefan Hofbauer, Louise N. Paton, Christian Obinger, Anthony J. Kettle,