| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8291080 | Archives of Biochemistry and Biophysics | 2012 | 8 Pages |
Abstract
⺠The major known mechanisms of action of therapeutic mAbs are summarized. ⺠The methods and problems with cell death and proliferation assays are reviewed. ⺠The assays and pitfalls of immune mediated activities of antibodies are reviewed. ⺠Whether in vitro and in vivo assays of antibodies predict clinical efficacy is discussed.
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Authors
Josée Golay, Martino Introna,