Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8291097 | Archives of Biochemistry and Biophysics | 2012 | 7 Pages |
Abstract
⺠Engineering of Fc with enhanced thermostability by an interchain disulfide bond. ⺠Combination with an intradomain disulfide bond further enhances stability. ⺠Applicable to wild-type Fc and to engineered, antigen-binding Fc. ⺠Biochemical and biophysical properties of stabilized Fc.
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Authors
Gordana Wozniak-Knopp, Florian Rüker,