| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8291306 | Archives of Biochemistry and Biophysics | 2012 | 7 Pages |
Abstract
⺠A reversible three-state unfolding of PLpro was identified. ⺠The zinc-binding domain starts to unfold during the first transition. ⺠Eighty percentage of activity loss at the first transition indicated the importance of zinc domain. ⺠PLpro displayed differential domain structure stability. ⺠The present studies help to understand the fold of other DUBs with similar scaffold.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Ya-Wen Chou, Shu-Chun Cheng, Hsing-Yi Lai, Chi-Yuan Chou,