| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8291360 | Archives of Biochemistry and Biophysics | 2012 | 6 Pages |
Abstract
⺠Suramin binds to thrombin through exosite 2. ⺠Suramin activates thrombin at low micromolar range. ⺠At higher suramin concentration thrombin is inhibited. ⺠A series of suramin analogs reveals the mechanism for activation and inhibition.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Maria Thereza Cargnelutti, Adriana Fonseca Marques, Daniel Esser, Robson Q. Monteiro, Matthias U. Kassack, Luis Mauricio T.R. Lima,