Article ID Journal Published Year Pages File Type
8291431 Archives of Biochemistry and Biophysics 2012 18 Pages PDF
Abstract
► We model renal ischemia-reperfusion injury in LLC-PK1 cells. ► We study the viability changes to compounds of LOPAC library. ► Adenosine exerts protection against oxygen-glucose deprivation injury. ► Adenosine receptors do not participate in the protective effect of adenosine. ► Adenosine kinase and adenosine deaminase play important roles in the cytoprotection.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: Purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia
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