Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8291468 | Archives of Biochemistry and Biophysics | 2011 | 9 Pages |
Abstract
⺠The NH2-terminal variable region of cardiac troponin T is a regulatory structure. ⺠Its removal has a compensatory effect on heart function in energetic crisis. ⺠Calcium overload conditions induced this restrictive proteolysis. ⺠The NH2-terminal structure of cardiac troponin forms a basis of this cleavage. ⺠Molecular conformation of the cleavage site may play a determining role.
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Authors
Zhiling Zhang, Han-Zhong Feng, J.-P. Jin,