Article ID Journal Published Year Pages File Type
8291482 Archives of Biochemistry and Biophysics 2011 10 Pages PDF
Abstract
► Niemann-Pick disease Type C and cystic fibrosis display abnormal storage of free cholesterol. ► Cholesterol storage affects many cellular functions and signaling pathways. ► Finding disease commonalities may lead to new therapeutic targets for both diseases.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Molecular pathways for intracellular cholesterol accumulation: Common pathogenic mechanisms in Niemann-Pick disease Type C and cystic fibrosis
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