Article ID Journal Published Year Pages File Type
8291534 Archives of Biochemistry and Biophysics 2011 10 Pages PDF
Abstract
► A pair of thiols in the vicinity of the dinucleotide-binding site can form a disulfide bond. ► Oxidized enzyme has a higher Kd for NAD+ and a much lower V/Et than wild type enzyme. ► Enzyme exists in two different forms, the disulfide and dithiol forms at low pH.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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