Article ID Journal Published Year Pages File Type
8291589 Archives of Biochemistry and Biophysics 2011 9 Pages PDF
Abstract
► ATP stimulates PI3K/Akt pathway in osteoblastic cell through P2Y2 receptors. ► PI-PLC, Ca2+, CaM and Src participate in Akt stimulation. ► PKC seems to regulate Akt through Src and the Ca2+ influx/CaM pathway. ► PI3K/Akt activation by ATP is involved in osteoblastic cell proliferation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Activation of the PI3K/Akt signaling pathway through P2Y2 receptors by extracellular ATP is involved in osteoblastic cell proliferation
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