Article ID Journal Published Year Pages File Type
8291610 Archives of Biochemistry and Biophysics 2011 11 Pages PDF
Abstract
► Mycobacterium tuberculosishisD-encoded histidinol dehydrogenase (MtHisD) is a dimeric metalloenzyme. ► MtHisD follows a Bi Uni Uni Bi Ping-Pong mechanism. ► l-Histidinol binds to free MtHisD. ► The imidazole group of His336 plays a critical role in catalysis and l-histidinol binding.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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