| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8291610 | Archives of Biochemistry and Biophysics | 2011 | 11 Pages |
Abstract
⺠Mycobacterium tuberculosishisD-encoded histidinol dehydrogenase (MtHisD) is a dimeric metalloenzyme. ⺠MtHisD follows a Bi Uni Uni Bi Ping-Pong mechanism. ⺠l-Histidinol binds to free MtHisD. ⺠The imidazole group of His336 plays a critical role in catalysis and l-histidinol binding.
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Authors
José E.S. Nunes, Rodrigo G. Ducati, Ardala Breda, Leonardo A. Rosado, Bibiana M. de Souza, Mario S. Palma, Diógenes S. Santos, Luiz A. Basso,