| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8291615 | Archives of Biochemistry and Biophysics | 2011 | 6 Pages |
Abstract
⺠A dimeric variant of DHDPS from Mycobacterium tuberculosis was engineered. ⺠The tertiary fold was preserved, but the quaternary structure was fully disrupted. ⺠Surprisingly, the activity was essentially conserved.
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Authors
Genevieve Evans, Linda Schuldt, Michael D.W. Griffin, Sean R.A. Devenish, F. Grant Pearce, Matthew A. Perugini, Renwick C.J. Dobson, Geoffrey B. Jameson, Manfred S. Weiss, Juliet A. Gerrard,