| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8291623 | Archives of Biochemistry and Biophysics | 2011 | 7 Pages |
Abstract
⺠Nitrogen dioxide (NO2) is an important oxidant molecule in biology. ⺠An in silico approach was used to estimate the solubility of NO2 in lipid membranes not experimentally accessible. ⺠A partition coefficient of 1.5 (membrane/water) was estimated, indicating NO2 is moderately hydrophobic. ⺠A membrane permeability coefficient of 5 cm s-1 was estimated, up to 4000 times higher than peroxynitrous acid. ⺠Lipid membranes are not significant barriers to NO2 transport.
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Authors
Santiago Signorelli, MatÃas N. Möller, E. Laura Coitiño, Ana Denicola,