| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8291643 | Archives of Biochemistry and Biophysics | 2011 | 7 Pages |
Abstract
⺠CYP51F1 from C. albicans successfully converted lanosterol to its demethylated product. ⺠The azole antifungal agents bound tightly to CYP51F1. ⺠The azole Kd values of the purified mutants identified in clinical isolates were little altered.
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Authors
Hyoung-Goo Park, Im-Soon Lee, Young-Jin Chun, Chul-Ho Yun, Jonathan B. Johnston, Paul R. Ortiz de Montellano, Donghak Kim,