Article ID Journal Published Year Pages File Type
8291758 Archives of Biochemistry and Biophysics 2011 7 Pages PDF
Abstract
► Vitamin D suppresses LPS- or TNFα- induced PAI-1 expression. ► A functional cis-κB element is identified in the mouse PAI-1 gene promoter. ► NF-κB mediates the stimulatory effect of LPS and TNFα on PAI-1. ► Vitamin D suppresses PAI-1 up-regulation via blocking NF-κB activation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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