Article ID Journal Published Year Pages File Type
8291795 Archives of Biochemistry and Biophysics 2011 8 Pages PDF
Abstract
► TOX4/PNUTS/WDR82 complex interacts with DNA damaged by anticancer platinum drugs. ► SPRi shows that TOX4 affinity for platinum adducts is weaker than that of HMGB1. ► Plasmid probes and proteomics allow identification of damaged DNA interactome.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs
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