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Suppression of cleavage factor Im 25 promotes the proliferation of lung cancer cells through alternative polyadenylation

Article ID Journal Published Year Pages File Type
8292353 Biochemical and Biophysical Research Communications 2018 7 Pages PDF
Abstract
Our findings suggest that CFIm25 plays an important role in lung cancer cell proliferation through regulating the APA of oncogenes, including IGF1R, and promoting their protein expression.
Keywords
p53IGF1RGSK3βA549CyclinD1Alternative polyadenylationProliferationApoptosisCancer
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Suppression of cleavage factor Im 25 promotes the proliferation of lung cancer cells through alternative polyadenylation
Authors
Jingjing Huang, Tingting Weng, Junsuk Ko, Ning-yuan Chen, Yu Xiang, Kelly Volcik, Leng Han, Michael R. Blackburn, Xiang Lu,
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Journal
Biochemical and Biophysical Research Communications
Journal: Biochemical and Biophysical Research Communications
Related Categories
p53
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