| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8292794 | Biochemical and Biophysical Research Communications | 2018 | 7 Pages |
Abstract
Our data indicate that SIN-1 induces FGF8 and FGFR3 overexpression and this is involved in the abnormal terminal differentiation and degradation of the ECM in cartilage. FGF8 and FGFR3 may therefore play an important role in the onset of deep zone necrosis and pathogenesis in KBD in adolescent children.
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Authors
Huizhong Liu, Qian Fang, Mengying Wang, Wenjun Wang, Meng Zhang, Dan Zhang, Ying He, Ying Zhang, Hui Wang, Miguel Otero, Tianyou Ma, Jinghong Chen,