Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8293098 | Biochemical and Biophysical Research Communications | 2018 | 8 Pages |
Abstract
L1-Tg/LDLRâ/â mouse is a humanized model to study cholesterol absorption and transportation. The results obtained from L1-Tg/LDLRâ/â mouse indicated no feedback mechanism to inhibit NPC1L1 function in liver and hepatic expression of NPC1L1 correlated with VLDL secretion in hypercholesterolemia state.
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Authors
Youlin Wang, Weiqing Tang, Pan Yang, Hyunsu Shin, Qingwang Li,