Article ID Journal Published Year Pages File Type
8293098 Biochemical and Biophysical Research Communications 2018 8 Pages PDF
Abstract
L1-Tg/LDLR−/− mouse is a humanized model to study cholesterol absorption and transportation. The results obtained from L1-Tg/LDLR−/− mouse indicated no feedback mechanism to inhibit NPC1L1 function in liver and hepatic expression of NPC1L1 correlated with VLDL secretion in hypercholesterolemia state.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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