| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8296112 | Biochemical and Biophysical Research Communications | 2017 | 6 Pages |
Abstract
In summary, pyruvate diminishes the cytotoxic activity of ascorbic acid in vitro. The AFR concentration measured remains unaffected by pyruvate whereas the H2O2 concentration is reduced; confirming that pyruvate directly reacts with AA-induced H2O2, without influencing its formation. However, further experiments are needed to elucidate the complex mechanisms being responsible for the reduced efficacy of AA in vivo.
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Authors
Sandra Rodemeister, Katharina Hill,