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Effect of the changes of NMDA receptor in hypothalamic paraventricular nucleus on cardiac function and sympathetic nervous activity in rats with heart failure

Article ID Journal Published Year Pages File Type
8296232 Biochemical and Biophysical Research Communications 2017 27 Pages PDF
Abstract
NMDAR1 is significantly activated in PVN of HF rats, the activity of TH is increased, GAD67 is downregulated, RSNA is increased, and the heart function is decreased. NMDA receptor blockers can alleviate HF.
Keywords
glutamic acid decarboxylase 67N-methyl-d-aspartate receptor 1tyrosine hydroxylaseRenal sympathetic nerve activityheart failure
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Effect of the changes of NMDA receptor in hypothalamic paraventricular nucleus on cardiac function and sympathetic nervous activity in rats with heart failure
Authors
Yaojun Sun, Bingyi Sun, Rongli He,
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Journal
Biochemical and Biophysical Research Communications
Journal: Biochemical and Biophysical Research Communications
Related Categories
glutamic acid decarboxylase 67
N-methyl-d-aspartate receptor 1
tyrosine hydroxylase
Renal sympathetic nerve activity
heart failure
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