Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8297829 | Biochemical and Biophysical Research Communications | 2013 | 20 Pages |
Abstract
⺠Substantial reducing equivalents are lost in human P450 CYP3A4 via an oxidase channel. ⺠Substrate binding has a pronounced effect on uncoupling in cytochrome P450. ⺠Anionic phospholipids improve the overall coupling in CYP3A4 Nanodiscs.
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Authors
Yelena V. Grinkova, Ilia G. Denisov, Mark A. McLean, Stephen G. Sligar,