| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8297915 | Biochemical and Biophysical Research Communications | 2013 | 6 Pages |
Abstract
⺠Acidosis inhibits amino acid (AA) starvation-induced cell death of WEHI7.2 cells. ⺠AA starvation-mediated induction of PUMA and Bim requires CHOP. ⺠AA starvation-mediated induction of PUMA additionally requires c-Jun. ⺠Acidosis inhibits AA starvation-mediated c-Jun elevation.
Keywords
GCN2B cell lymphoma-2ATFBcl-2AARPHEGPCRBcl-2-interacting mediator of cell deathPARPAPAf-1eIF2αMdm2Extracellular pHapoptotic protease-activating factor-1Amino acidsAcidosisBaxCHOPc-JunApoptosismurine double minute 2activating transcription factorBIMBcl-2-associated X proteinCCAAT/enhancer-binding protein homologous proteinpoly-(ADP-ribose) polymerasePUMAG protein-coupled receptor
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Authors
Christopher B. Ryder, Karen McColl, Clark W. Distelhorst,