Article ID Journal Published Year Pages File Type
8297975 Biochemical and Biophysical Research Communications 2011 5 Pages PDF
Abstract
► The N-terminal domain of hIno80 is important for binding to the spindle. ► The hIno80 N-terminal domain binds to tubulin and microtubule in vitro. ► The E-hook of tubulin is critical for hIno80 binding to tubulin and microtubule. ► Tip49a does not bind to microtubule and dispensable for spindle formation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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The human Ino80 binds to microtubule via the E-hook of tubulin: Implications for the role in spindle assembly
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