Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8297977 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠TRUE gene silencing is a novel technology for suppressing gene expression. ⺠This is based on the property that tRNase ZL can cleave any target RNA under the aegis of artificial sgRNA. ⺠We expanded the utility of sgRNA through LNA modifications and usage of double heptamers.
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Authors
Takako Sano, Masayuki Takahashi, Tadasuke Nozaki, Yoshiaki Takahashi, Masato Tamura, Masayuki Nashimoto,