Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8297986 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠JAK/STAT activity is graded in the Drosophila optic lobe neuroepithelium. ⺠Inactivation of JAK signaling causes disintegration of the optic lobe neuroepithelium and depletion of the neuroepithelial stem cells. ⺠JAK pathway overactivation promotes neuroepithelial overgrowth. ⺠Notch signaling acts downstream of JAK/STAT to promote neuroepithelial growth and expansion.
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Authors
Wei Wang, Yonggang Li, Liya Zhou, Haitao Yue, Hong Luo,