Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8298105 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠We propose a simple stochastic model to construct primitive DNA sequences. ⺠The model provide an explanation for Chargaff's second parity rule in primitive DNA sequences. ⺠The model is also used to predict a novel type of strand symmetry in primitive DNA sequences. ⺠We extend the results for bacterial DNA sequences and compare distributional properties intrinsic to the model to statistical estimates from 1049 bacterial genomes. ⺠We find out statistical evidences that the novel type of strand symmetry holds for bacterial DNA sequences.
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Authors
Marcelo Sobottka, Andrew G. Hart,