Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8298129 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠GATA-3 expression and phosphorylation of STAT6 were lost in Th2 LCR-deficient cells. ⺠The gata3 locus is in an inactive status in these cells. ⺠The gata3 locus was bound and activated by GATA-3 itself and STAT6. ⺠Thus gata3 expression in Th2 cells is regulated by a feed-forward mechanism.
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Authors
Soo Seok Hwang, Kiwan Kim, Gap Ryol Lee,