Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8298152 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠HOCl-LDL promotes apoptosis and accumulation of ROS in T-cells. ⺠Apoptosis occurs via intrinsic routes confirmed by FADDdef or Casp-8def cells. ⺠Overexpression of Bcl-2 protects T-cells from apoptosis and ROS formation. ⺠HOCl-modified epitopes colocalize with MPO and T-cells in human placental tissue.
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Authors
Ulrike Resch, Michaela Semlitsch, Astrid Hammer, Heidrun Susani-Etzerodt, Henning Walczak, Wolfgang Sattler, Ernst Malle,