| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8298163 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠By using RNA interference, fluid secretion from the isolated guinea-pig pancreatic duct cells is markedly decreased to â¼50% of control. ⺠Both CFTR and aquaporin 1 expression were decreased when CFTR expression was inhibited by RNA interference. ⺠This reduction of fluid secretion can be seen as a cause of developing chronic pancreatitis.
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Authors
Shigeru B.H. Ko, Akiko Yamamoto, Sakiko Azuma, Haizhen Song, Kaori Kamimura, Miyuki Nakakuki, Michael A. Gray, Frédéric Becq, Hiroshi Ishiguro, Hidemi Goto,