Article ID Journal Published Year Pages File Type
8300034 Biochimica et Biophysica Acta (BBA) - Biomembranes 2012 6 Pages PDF
Abstract
► We examine the positioning of neuronal-Synaptobrevin within micelles. ► Mutants with zero and two Trp residues are compared to wild-type (one Trp). ► Mutations of juxtamembrane tryptophan residues affect membrane positioning. ► Decreasing Trp content results in deeper immersion of the peptide in the micelle ► Increasing Trp content dampens peptide dynamics near the water-micelle interface.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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