Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300034 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 6 Pages |
Abstract
⺠We examine the positioning of neuronal-Synaptobrevin within micelles. ⺠Mutants with zero and two Trp residues are compared to wild-type (one Trp). ⺠Mutations of juxtamembrane tryptophan residues affect membrane positioning. ⺠Decreasing Trp content results in deeper immersion of the peptide in the micelle ⺠Increasing Trp content dampens peptide dynamics near the water-micelle interface.
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Authors
M. Sameer Al-Abdul-Wahid, Colin M. DeMill, Marzena B. Serwin, R. Scott Prosser, Bryan A. Stewart,