Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300038 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 10 Pages |
Abstract
⺠We describe the effect of two novel natural lipopeptides, anabaenolysin A and B. ⺠Abl A and B completely lyse the membrane of mammalian cells, but leave the mitochondria intact. ⺠Abl A is a more potent haemolysin than digitonin and surfactin. ⺠Abl A permeabilises membranes in a cholesterol-dependent manner. ⺠Abl A and B show a structural similarity to digitonin.
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Authors
Linn Oftedal, Lene Myhren, Jouni Jokela, Gro Gausdal, Kaarina Sivonen, Stein Ove Døskeland, Lars Herfindal,