Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8300044 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 9 Pages |
Abstract
⺠Membrane location of 4 local anesthetics was studied by quantitative 1H MAS NMR. ⺠Aromatic rings of all local anesthetics are located in the lipidâwater interface. ⺠Small difference in the membrane location originate from molecular structures. ⺠Hydrophobic side chains of dibucaine and tetracaine are inserted into the membrane.
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Authors
Nicole Weizenmann, Daniel Huster, Holger A. Scheidt,